CVS Pharmacology mcqs for jobs test preparation in pharmacology departments.
CVS Pharmacology MCQs
Mechanism of action of nifidipine is ____?
A. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure
B. Nifidipine depresses the SA node thus decreasing mycocoardial excitability
C. Mainly depression of A-V conduction
D. Decreased cardiac output thus decreasing load on myocardium
The mechanism of action of sodium nitroprusside is _____?
A. Increases cAMP
B. Direct Vasodilator
C. Calcium channel blocker
D. Block the sympathetic flow at hypothalamus
Morphine is a _____?
A. Sedative
B. Alkaloid
C. Diuretic
D. Anti hypertensive
E. Both A & B
Which of the following cardiac depressants is contraindicated in a patient with cardiac arrhythmia ____?
A. Lidocaine
B. Quinidine
C. Phenytoin
D. Propranolol
The potent anti arrhythmic drug which has little negative ionotropic effect valuable in patients with poor left ventricular function _____?
A. Amlodipine
B. Bidoprolo
C. Amiodarnone
D. Digoxin
The following drugs are useful in hypertension except ______?
A. Calcium channel blockers
B. Alpha methyl dopa
C. Beta blockers
D. Pentoxifyline
Hypokalemia is seen in therapy with ______?
A. Digitalis
B. Ibuprufen
C. Corticosteroids
D. Diazepam
Alpha blocker used as anti hypertensive agent ______?
A. Alpha methyl DOPA
B. Prazosin
C. Clonidine
D. Propranolol
Isosorbide 5 – mononitrate is preferred because ____?
A. Less tolerance develops
B. Sublingual absorption is better
C. Longer duration of action
D. Direct coronary vasodilatory action is more
All of the following drugs are useful in treatment of hypertension except ______?
A. Ephedrine
B. Reserpine
C. Methyldopa
D. Thiazole diuretics
Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine _____?
A. Propranolol
B. Hydralazine
C. A thiazide diuretic
D. Gauanethidine
Bradycardia is most commonly treated with which of the following drugs _______?
A. Epinephrine
B. Atropine
C. A diuretic
D. A potent vasadilatior
Blockers are used in all except ______?
A. Phenochyromocytoma
B. Migraine
C. Thyrotoxcosis
D. Secondary shock
Beta2 adrenergic receptor stimulating drugs are used in _______?
A. Bronchial asthma
B. cardiac asthma
C. Hypertension
D. Angina pectrosis
Which of the following is antiasthmatic ____?
A. Histamine
B. Salbutamol
C. Acetylcholine
D. Serotonin
Bronchospasm can be precipitated by ________?
A. Adrenaline
B. propranolol
C. Atropine
D. Salbutamol
Magnesium and Aluminium are added in Antacid because ___?
A. Mg Causes constipation, Al causes diarrhoea
B. Mg Causes Diarrhoea, Al Causes Constipation
C. Mg act as buffering agent and Al antagonize its action
D. Both increase gastric motility
Each of the following is correct for the treatment of Diarrhoea except _____?
A. Kaolin has marginal therapeutic effect
B. Opioids delay the passage of gut contents by decreasing peristalsis and increasing intestinal segmentation
C. Loperamide had high abuse potential
D. Diphenoxylate may cause respiratory depression on administration
Omeprazole is a ____?
A. Antihistamine
B. Proton pump inhibitor
C. Ulcer protective
D. Ulcer healing drug
Doalin pectrose is ____?
A. Mummifying agent
B. Anticoagulant
C. Counter irritant
D. Anti diarroheal
Omeprazol is used in the treatment of ____?
A. Peptic Ulcer
B. Amoebiasis
C. Malaria
D. cholera
Which of the following is an ACE inhibitor ?
A. Saralosin
B. Diltiazem
C. Coptopril
D. Spirino lactone
Following inhibits Cytochrome P450 _____?
A. Cimetidine
B. Famotidine
C. Ranitidine
D. All of the above
Which one of the following drugs is most commonly employed in an attack of angina pectoris ?
A. Sodium nitrate
B. Epinephrine
C. Nitroglycerina
D. Isosorbide dinitrate
Long acting beta – 2 agonist ?
A. Albuterol
B. Salmeterol
C. Pirlbuterol
D. Orciprenaline
Which one of the following is Not true of angiotensin converting enzyme (ACE) inhibitor ____?
A. May cause hyperkalaemia in diabetic patients
B. Contraindicated in pregnancy
C. Contraindicated in diabetic nephropathy
D. NSAIDs may impair its hypotensive effect
Ipratropium bromide is used for _____?
A. Renal colic
B. Organophosphorus poisoning
C. Bronchial asthma
D. miosis
All of the given drugs are positive inotropes EXCEPT _____?
A. Dopamine
B. dobutamine
C. Digoxin
D. Doxepin
Which one is not converted to an active metabolite ?
A. Quinapril
B. Fosinopril
C. Benzopril
D. Lisinopril
Which one of the anti hypertensives is contraindicated in pregnancy ?
A. Hydralazine
B. a-Methldopa
C. Nifedipine
D. Enlapril
Which of the following is a protective drug in the management of gastric and duodenal ulcers ?
A. H2 antihistamines
B. NaHCO3
C. Famotidine
D. Carbenoxolone
Which of the following is not an antimigraine agent ?
A. Flunarizine
B. Divalprox sodium
C. Zonisamide
D. Propanolol
About heparin true is ___?
A. Mixture of sulphated polypeptide
B. Known to cause idiopathic thrombocytosis
C. Half-life is 90 min
D. Decrease action of prothrombin III
Which of the following statements regarding nitroglycerin is true ?
A. The effect is more pronounced in venous
B. High membrane penetrability
C. Poorly suited for oral administration
D. All of the above
A young lady talking rifampicin and OCP together become pregnant, most probable cause is _______?
A. Rifampicin causes hepatic enzyme induction and increase metabolism of OCP’s
B. Decreased absorption of OCP’s
C. Obstruction of fallopian tubes
D. Increase excretion of OCP’s
Which of the following is not true about ACE inhibitors ?
A. Used in asthma
B. Increase quality of life
C. Postural hypotension is seen
D. Na level decrease
Diuretics cause loss of ______?
A. Sodium
B. Calcium
C. Potassium
D. Iron
Heroin, an addict drug contains ____?
A. ASA
B. Acetyl morphine
C. Pentazocine
D. Propoxyphene
Which of the following is not caused by Frusemide _______?
A. Hypokalemia
B. Hyperuricemia
C. Hypercalcemia
D. Hyponatremia
Action of Nitroglycerin is _______?
A. Direct action on smooth muscle
B. Slows SA node conductivity
C. Blocks arrhythmia
D. Increases perfusion to heart
Beta blockers are contraindicated in ___?
A. Angina pectoris
B. Cardiac arrhythmia
C. Cardiac failure
D. Myocardial infarction
Which of the following sympathominetic agents is the most bronchodilator ____?
A. Amphetamine
B. Nor epinephrine
C. Isoproterenol
D. Phenylephrine
Which one of the following drugs is not contraindicated in bronchial asthma ?
A. Morphine
B. Propanolol
C. Stropine
D. Nitroglycerine
All the following about antiemetic drugs are correct except _____?
A. Domperidone blocks the D2 receptors in CTZ and upper gut
B. Domperidone causes Dystonia
C. Ondastran acts on selective 5 -HT3 receptors
D. Ondastran may cause vomiting by effecting the cytotoxic antige receptors
INFLIXIMAB (systemic) is used in _____?
A. Crohn’s disease (treatment)
B. To reduce the number of draining enterocutaneous fistula(s) in patients with fistulizing crohn’s disease
C. Rheumatoid arthritis (treatment)
D. All of the above
One of the following is not an antiemetic ____?
A. Chlorpromazine
B. Digitoxin
C. Metaclopromide
D. Scopolamine
Salbutamol is used in ______?
A. Cardiac asthma
B. Bronchial asthma
C. Pulmanray oedema
D. Cor pulmonale
Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of reflex ?
A. Ondansetron
B. Metoclopramide
C. Sodium citrate
D. Atropine
All of the following are predominant arteriolar dilators except _____?
A. Sodium Nitro prusside
B. Hydrallazine
C. Nifedipine
D. Nitrates
All of the given drugs may be useful in acute exacerbation of bronchial asthma EXCEPT ______?
A. Cromolyn sodium
B. Hydrocortisone
C. Salbutamol
D. Ipratropium
Drug not requiring dose adjustment in renal disease is _____?
A. Aminoglycoside
B. Vancomycin
C. Calcium channel blocker
D. Metronidazole
All the following drugs reduced the gastric acid secretion EXCEPT ____?
A. Ranitidine
B. Sucralfate
C. Misoprostal
D. Pantoprazole
B- blocker with additional a-blocking property is __?
A. Propranolol
B. Timolol
C. Metoprolol
D. Labetalol
Which is not antiemetic ?
A. Domperidone
B. Phenazocine
C. Cyclizine
D. Ondanestron
Read More: Pharmacology Past Papers