Prepare for chemotherapy-related exams with our comprehensive collection of chemotherapy MCQs, curated for one paper mcqs test preparation.
Chemotherapy MCQs with Answers
The most common side effect of the oral administration of ampicillin is :
A. Anaphylactic shock
B. Diarrhoea
C. Oral candidiasis
D. Renal failure
Which of the following is primarily a bactericidal drug?
A. Chloramphenicol
B. Gentamicin
C. Sulphadiazine
D. Tetracycline
The therapeutic advantage that penicillin V has over penicillin G is?
A. More reliable oral absorption
B. Greater resistance to penicillinase
C. Slower renal excretion
D. Broader antibacterial spectrum
Chloramphenicol can cause :
A. Staining of teeth
B. Aplastic anaemia
C. Bone marrow suppression
D. B & C
The antibiotic of choice in patients sensitive to penicillin is ?
A. Erythromycin
B. Streptomycin
C. Tetracycline
D. Chloramphenicol
Tetracycline is contraindicated in :
A. Children
B. Pregnancy
C. Renal failure
D. All of the above
Mechanism of action of quinolones is:
A. Inhibits DNA gyrase
B. Inhibits Bacterial protein synthesis
C. Inhibits bacterial cell wall synthesis
D. Inhibits intake of folic acid
The bacterial resistance to tetracycline is due to:
A. Alteration of drug binding sites
B. Alteration of dehydrofolate reductase
C. Inactivation of drug by enzymes
D. Decreased uptake of drug by bacteria
The drug of choice for treatment of typhoid is:
A. Tetracycline
B. Metronidazole
C. Ciprofloxacin
D. Cefotaxim
Antifungal drug not used in the treatment of intestinal candidiasis:
A. Amphotericin
B. Nystatin
C. Ketoconazole
D. Clotrimazole
Desfuroxamide is a drug used for:
A. Kala azar
B. Pernicious anaemia
C. Pain control
D. Thalassemia
Which on of the following is penicillinase resistant penicillin _______?
A. Amoxycillin
B. Cloxacillin
C. Ampicillin
D. Penicillin G
The drug which gives orange colour to the urine is _____?
A. Rifampicin
B. Ethambutol
C. INH
D. Streptomycin
In the treatment of intestinal of intestinal and extra intestinal amoebiasis which of the following drug is useful ____?
A. Diloxane
B. Metronidazole
C. Chloroquine
D. Cefaclor
Which one of the following antibiotics chelates with calcium ?
A. pencillin
B. Tetracycline
C. Cephalosporins
D. Erythromycin
Combination chemotherapy is used in tuberculosis in order to reduce _____?
A. Side effects of drugs
B. Cost of therapy
C. Dosage of drugs
D. Development of drug resistance
One of the below mentioned penicillin is NOT given orally ___?
A. Amoxicillin
B. Carbenicillin
C. Cloxacillin
D. Phenoxymethy penicillin
Ototoxicity and nephrotoxicity is caused by:
A. Antiemetic
B. Antiviral
C. Antifungal
D. antibiotic
Which of the following penicillins is given by oral route ?
A. Benzyl penicillin
B. Benzathine penicillin
C. Procaine pencillin
D. Penicillin V / Phenoxymethyl penicillin
Stepwise mutation for drug resistance is seen with _____?
A. Penicillin
B. Streptomycin
C. Garamycin
D. Kanamycin
Oral infection by penicillinase producing organisms should be treated with __?
A. Ampicillin
B. Dicloxacillin
C. Erythromycin
D. Any of the above
Which of the following is caused by Amphotericin B ______?
A. Hypo Kalemia
B. Hyperkalemia
C. Hypermagnesemia
D. Hyponatremia
Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis ?
A. Isoniazid
B. Streptomycin
C. Ripampicin
D. Pyrazinamide
Optic neuritis is a side effect of _____?
A. Rifampicin
B. INH
C. Pyrazinamide
D. Ethambutol
Which of the following drug control lepramin reaction ____?
A. Dapsone
B. Streptomycin
C. Clofazimine
D. Ethambutol
The most serious side effect of drug colormap henicol is _____?
A. Candidiasis
B. Photosensitivity
C. Bone marrow depression
D. Angioneurotic oedema
Tetracycline is more preferred in periodontics because _____?
A. It is broad spectrum antibiotic
B. It has anticollagenolytic effect
C. All of the above
D. None of the above
Tetracycline in children causes _____?
A. Calcification
B. Missing teeth
C. Discolored teeth
D. Peg teeth
Drug which is most unsafe during pregnancy is __?
A. Ethambutol
B. Streptomycin
C. Kanamycin
D. B & C
The aminoglycoside with least toxic effect is _______?
A. Ethambutol
B. Isoniazid
C. Streptomycin
D. Kanamycin
First line of antitubercular drug is:
A. Streptomycin
B. INH
C. Ethambutol
D. Cephalosporins
Cell wall synthesis is inhibited by all except:
A. Lincomycin
B. Penicillin
C. Cephalexin
D. Ampicillin
Metronidazole is a type of:
A. Broad spectrum antibiotic
B. Quinolone
C. Imidazole derivative
D. Antidepressant
Bacitracin is a _____?
A. Oral antibiotic
B. Topical antibiotic
C. Parenteral antibiotic
D. All of the above
Antibiotic that achieves high concentration in Hard tissue, because of its molecular size is ___?
A. Ceftum
B. Ciprofloxacin
C. Clindamycin
D. Erythromycin
Tetracycline chelates with ______?
A. Ca salts
B. Mg salts
C. All salts
D. All of the above
Phototoxicity is the side effect of :
A. Penicillin
B. Demeclocycline
C. Erythormycin
D. Streptomycin
Drugs producing ototoxicity and Nephro toxicity are:
A. Tetracyclines
B. Aminoglycosides
C. Quinalones
D. Macrolides
Which among the drugs given below, does Not act by protease inhibition ?
A. Ritonavir
B. Saquinavir
C. Nelfinavir
D. Zanamivir
Which of the following antibiotics is effective in treating oral candidiasis ?
A. Nystatin
B. Bacitracin
C. Penicillin
D. Tetracycline
Drug of choice in Amoebic liver abscess besides metronidazole is :
A. Ciprofloxacin
B. Chloroquin
C. Mebendazole
D. Bephenium Naphthoate
Traces of which of the antibiotics can be found in the gingival fluid after administration ____?
A. Tetracycline
B. Lincomycin
C. Clindamyclin
D. Penicillin G
The following are the indications for Metronidazole except _;
A. Ulcerative gingivitis
B. Amoebiasis
C. Trichomonas infection
D. Streptococcal sore throat
The following adverse effect of penicillin is dose related:
A. Skin rash
B. Intersititial Nephritis
C. Drug fever
D. Encephalopathy
One of the drug is betalactamase inhibitor ;
A. Ampicillin
B. Sulbactum
C. Cloxacillin
D. Pencillin G
Mechanism of action of chlortetracycline;
A. Interfere with metabolism
B. Inhibition of protein synthesis
C. Inhibition of cell wall formation
D. Interfere with DNA function
Ketoconazole ____?
A. Antifungal agent
B. Antibacterial
C. Antiviral agent
D. Chemotherapic agent
Agent used in oral thrush ____?
A. Miconazole
B. Clobetasol
C. Clotrimazole
D. Amoxycillin
All of the following cephalosporines are active against Pseudomonas Except:
A. Ceftazidine
B. Cefotaxime
C. Cefoperazone
D. Cefaclor
More potent and non toxic drug against herpes virus is :
A. Zidovodine
B. Acyclovir
C. Nystatin
D. Amontidine
Which among the following is the drug of choice for clostridium difficile induced colitis ?
A. Gentamicin
B. Ciprofloxacin
C. Metronidazole
D. Linezolid
Which anti tubercular drug will cause transient memory loss ?
A. Enthionamide
B. INH
C. Ethambutol
D. Pyrazinamide
Drugs which cause ototoxicity and circumoral paraesthesia are ___?
A. Antileprotic drugs
B. Antitubercular drugs
C. Streptomycin
D. Chloramphenicol
Drug to be avoided in a patient allergic to penicillin is _____?
A. Sulphonamide
B. Tetracycline
C. Ampicillin
D. Cholarmphenicol
Ivermectin is indicated in
A. Scabies
B. Intestinal nematode infection
C. Filariasis
D. All of the above
All except one are centrally acting muscle blocks
A. Meprobamate
B. Baclofen
C. Diazepam
D. Dantrolene sodium
All of the following drugs are contraindicated in patients with G-6-PD deficiency, except _____?
A. Cotrimoxazole
B. Furazolidone
C. Nalidixic acid
D. Ceftriaxone
All of the following are features of streptomycin drug except ____?
A. It is an antitubercular drug
B. It can be given orally
C. Effective against g-ve organisms
D. None of the above
All of the following drugs are primarily bacteriostatic except ____?
A. Sulphonamide
B. Chloramphenicol
C. Ethambutol
D. Rifampin
Which of the following penicillin’s has the best gram negative spectrum ?
A. Methicillin
B. Ampicillin
C. Penicillin V
D. Cefixime
Which of the following antibiotics is found at much higher concentrations in crevicular fluid than in serum ?
A. Clindamycin
B. Penicillin
C. Tetracycline
D. Metronidazole
Drug of choice to treat fungal infection in AIDS is _____?
A. Acyclovir
B. Ketoconazole
C. Aerosolized pentamidine
D. Didanasine
Erythromycin is ______?
A. Cidal in action
B. Cidal in high concentration
C. Static in action
D. All of these
Identify the drugs useful against pseudomonas’s infection ____?
A. Ticarcillin
B. Ceftazidine
C. Amoxycillin
D. All of the above
Amino glycosides _____?
A. Accumulate in renal failure
B. Inhibit protein synthesis
C. Effective against gram negative infection
D. All of the above
A potent non-toxic anti-herpes drug is :
A. Acyclovir
B. Vidarabine
C. Idoxyuridine
D. Ara-amp
Sulphonamides mainly interferes with the bacterial :
A. Transcription mechanisms
B. Translation
C. Ribosomal function
D. PABA
Which one of the following antibacterial should not be used with d-tubocurarine ?
A. Norfloxacin
B. Streptomycin
C. Doxycycline
D. Cefotaxime
Clavulanic acid is given in combination with amoxicillin in order to ____?
A. Reduce the risk allergic reactions:
B. Prolong amoxicillin’s half-life
C. Reduce the severity of diarrhea
D. Extend amoxicillin’s antibacterial spectrum
All of the following are therapeutic uses of penicillin G, except ____?
A. Bacterial meningitis
B. Rickettsial infection
C. Syphilis
D. Anthrax
The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is ____?
A. Tetracyclines
B. Polypeptide antibiotics
C. Fluoroquinolones
D. Macrolides
INH induced neuropathy is treated with _____?
A. Thiamine
B. Pyridoxine
C. Niacin
D. Riboflavin
Which of the following is not a broad spectrum antibiotic ?
A. Tetracycline
B. Chloramphenicol
C. Doxycyclin
D. Cephalosporins
Which of the following antibiotics is not used in the treatment of infectious mononucleosis ?
A. Ampicillin
B. Gentamycin
C. Erythromycin
D. Ciprofloxacin
Which of the following is associated with neutropenia ?
A. Doxorubicin
B. Vinblastin
C. Cisplastin
D. Methotrexate
Which of the following is third generation cephalosporin ?
A. Cefeperazone
B. Cefuroxime
C. Cefoxitin
D. Cefadroxil
Which drug can be safely used in lactating mothers ?
A. Ampicillin
B. Chloramphenicol
C. Ciprofloxacin
D. Erythromycin
Which of the most effective for drug asymptomatic amoebic cysts ?
A. Metronidazole
B. Diloxanide furoate
C. Quinidochlor
D. Furazolidone
Which among the following anti-HIV drugs in an inhibitor of viral fusion ?
A. Enfuvirtide
B. Nelfinavir
C. Efavirenz
D. Etanercept:
Colour of teeth stained by tetracycline appear ____ under UV light?
A. Red
B. Green
C. Yellow
D. Brown
Jerisch-Heximer reaction is treated by administering :
A. Intravenous Penicillin G
B. Antihistamines
C. Tetracyclines
D. Steroids
Which among the following anti-HIV drugs is also used to treat viral hepatitis B ?
A. Enfuvirtide
B. Lamivudine
C. Efavirenz
D. Ritonavir
Redman syndrome is side effect of:
A. Rifampicin
B. Vancomycin
C. Chloramphenicol
D. Tetracycline
Amphotericin B is given for what:
A. Fungal
B. Viral
C. Bacterial
D. Rickettesial
Which of the following is beta-lactam antibiotic ?
A. Sulphonamide
B. Carbamide
C. Cephalosporins
D. Ofloxacin
1st generation cephalosporin is _____?
A. Cephadroxil
B. Cefepime
C. Cefotaxime
D. Cefoperazone
Not true about piperacilline is ______?
A. Active against pseudomonas aeruginose
B. Inhibits Beta-lactamase
C. It is a ureido penicillin
D. Given parenterally
Roxithromycin is ____?
A. A long acting macrolide
B. Short action quinolone
C. Short acting macrolide
D. Long acting polypeptide
Which of the following is not uridopenicillin ?
A. Piperacillin
B. Mezlocillin
C. Azlocillin
D. Flucloxacillin
Tetracyclines act by _____?
A. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex
B. Inhibiting peptidyl transferase
C. Inactivating elongation factors
D. Causing misreading of mRNA
The incidence of allergy to penicillin among various population ranges from :
A. 1% to 10%
B. 10% to 20%
C. 20% to 30
D. 30% to 40%
The most preferred acute emetic for emesis induced by anticancer drugs is:
A. Ondensetron
B. Metaclopromide
C. Chlorpromazine
D. Dicyclomine
Not true about PnG is __?
A. Destroyed by gastic acid
B. Very active against sensitive gram positive coci
C. Used for treatment of meningococcal meningitis
D. More concentrated in prostatic secretion and intraocular fluids
All are macrolide antibiotics EXCEPT _____?
A. Erythromycin
B. Roxithromycin
C. Neomycin
D. Calithromycin
Which of the following can be given as a single dose antimalarial for P.vivax malaria __?
A. Atovaquone + Proguanil
B. Artemisinin
C. Quinine + Tetracycline
D. Pyrimethamine + Sulfadoxime
Tetracycline acts on ____?
A. 30S ribosomes
B. 50S ribosomes
C. Cell membrane
D. Inhibiting DNA gyrase
AIDS is a disease if the immune system primarily affecting ______?
A. Granulocytes
B. Immunoglobulins
C. Opsonins
D. T lymphocytes
Topical Antifungal agent in candidiasis is _____?
A. Clotrimazole
B. Clotrimoxazole
C. Ornidazole
D. Propronolol
Which of the following drug does not show renal toxicity ______?
A. Gentamycin
B. Streptomycin
C. Methoxyprenaline
D. Isoflurane
Nevirapine is a ______?
A. Protease inhibitor
B. Nucleoside reverse transcriptase inhibitor
C. Non-nucleoside reverse transcriptase inhibitor
D. Fusion inhibitor
All of the following antibacterial agents acts by inhibiting cell wall systhesis except ___?
A. Carbapenems
B. Monobactams
C. Cephamycins
D. Nitrofurantoins
One of the following is not penicillinase susceptible ______?
A. Amoxicillin
B. Penicillin G
C. Piperacillin
D. Cloxacillin
All of the following are topically used sulphonamides except ____?
A. Suphacetamide
B. Sulphadiazine
C. Silversulphadiazine
D. Mafenide
Cephalosporin active against pseudomonas aeruginosa ;
A. Cefoperazone
B. Cefaclor
C. Ceftriaxone
D. Cefotaxime
Which one of the following drugs is an antipseudomonal penicillin ?
A. Cephalexin
B. Cloxacillin
C. Piperacillin
D. Dictoxacillin
All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT _____?
A. Procarbazine
B. Vincristine
C. Mechlorethamine
D. Methotrexate
Disseminated candidiasis requires intensive therapy with ______?
A. Nystatin
B. Amphotericin
C. Interferons
D. Thiobendazole
B-lactam antibiotics are _____?
A. Penicillin
B. Imipenem
C. Cephalosporins
D. All of the above
Povidine iodine is used for;
A. Burns
B. Tinea
C. Non-specific vaginitis
D. All of the above
An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is;
A. Gentamycin
B. Tetracycline
C. Aztreonam
D. Neomycin
True about amoxycillin in comparison to ampicillin is ;
A. Higher oral biovailability
B. Lower oral biovailability
C. Equal oral biovailability
D. Can be given Parenterally
The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly ______?
A. Anaerobic
B. Gram positive organism
C. Gram negative organisms
D. Yeast and fungi
Cross resistance of isoniazid is seen with _____?
A. Rifampicin
B. Ethionamide
C. Cycloserine
D. Ethambutol
Metronidazole ______?
A. Has no side-effects
B. Is used in management of ANUG
C. Is mainly concentrated in saliva
D. Is active against gram-positive aerobes
Which of the following is a 4th generation cephalosporin ___?
A. Ceftrioxone
B. Cefaclor
C. Cefepime
D. Cefuroxime
Cyclosporine is used an ____?
A. Anticancer drug
B. Antibiotic
C. Antiarrhythmic
D. Immunosuppresant
Best treatment of candidiasis of ______?
A. Myostatin
B. Amphoterin
C. Antibiotics
D. None of the above
Which of the following is a first generation oral cephalosporin _____?
A. Cephapirin
B. Cefadroxil
C. Cefaclor
D. Cefixime
True about aminoglycoside is all except ______?
A. Are bacteriostatic
B. Distributed only extracellularly
C. Excreted unchanged in urine
D. Teratogenic
Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
A. Ethambutol
B. Isoniazid
C. Rifampicin
D. Streptomycin
Penicillin is effective against _____?
A. Neisseria meningitis
B. Neisseria gonorrhoeae
C. Treponema Pallidum
D. All of the above
Concurrent administration of tetracyclines is most likely to impair the action of _____?
A. Lincomycin
B. Chloramphenicol
C. Erythromycin
D. Penicillin
Which drug causes photosensitivity _____?
A. Tetracycline
B. Aminoglycoside
C. Penicillin
D. Cephalosporin
Which of the following penicillins can be given by IV route ?
A. Benzathine
B. Procaine
C. Crystalline
D. Benzathamine
Fluconazole is used for the treatment of _______?
A. Pemphigus
B. Herpes simplex
C. Candidiasis
D. Syphilis
A child with permanently stained teeth reports, He was most probably administered _____?
A. Disphenyl hydantoin
B. Diphenhydramine
C. Digoxin
D. Doxycycline
A patient suffering from syphilis is given pencillin He may develop ___?
A. Cholestatic Jaundice
B. Grey Syndrome
C. Fanconi Syndrome
D. Jarish – Herxheimer reaction
Peripheral neuritis is a complication of
A. Isoniazid
B. Ethambutol
C. Rifampicin
D. Pirazinamide
The mechanism of action of chloramphenicol is inhibition of synthesis of ____?
A. Cell wall
B. Cell membrane
C. Protein
D. DNA
A patient taking which of the following drug should not eat cheese, etc ___?
A. Tetracycline
B. Amoxycillin
C. Doxycycline
D. Triamterene
Prolonged administration of streptomycin may result in damage to the ____?
A. Optic nerve
B. Facial nerve
C. Auditory nerve
D. Trigeminal nerve
Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?
A. Ampicillin
B. Penicillin
C. Clindamycin
D. Cephalosporin
A distinict advantage that tetracyclines have over penicillin’s is that tetracyclines _____?
A. Have no side effects
B. Do not cause superinfections
C. Are safer to use during pregnancy
D. Have a wider range of antibacterial activity
Which antibiotic is effective against pseudomonas and indole +ve proteus ?
A. Methicillin
B. Carbenicillin
C. Lincomycin
D. Oxacillin
Antibiotic that interferes with DNA function is _____?
A. Metronidazole
B. Nystatin
C. Tetracycline
D. Sulphonamides
The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is ______?
A. Ampicillin
B. Erythromycin
C. Pencilling G
D. Methicillin sodium
Drug chemically related to penicillin’s is :
A. Tetracycline
B. Sulphonamide
C. Cephalosporin
D. Lincemycin
Read More: Review Pharmacology MCQs for effective online test preparation. Strengthen your knowledge and boost your exam readiness with our comprehensive question set.
Notes: All these chemotherapy MCQs have been frequently featured in past exams, making them ideal for effective test preparation and review.
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