ANS Pharmacology MCQs for test preparation of jobs in pharmacology departments.
ANS Pharmacology MCQs
The intramuscular administration of 0.6 mg of atropine sulphate to a 50 – kg adult may produce all of the following effects except _______?
A. Bradycardia
B. Decreased Salivation
C. Decreased Sweating
D. Mydriasis
All of the following drugs are non depolarizing neuromuscular blocking agents except _________?
A. D-tubocurarine
B. Gallamine triethiodide
C. Pancuronium bromide
D. Succinylcholine
Which of the following group of drugs are a neuromuscular blocking agents ______?
A. choline, adrenaline and amphetamine
B. Glycinium neostigamine and physostigamine
C. Pancuronium, rocuronium
D. Pirenzipine, propanolol and propantheline
The metabolic effects of sympathomimetics are mediated by ______?
A. All beta-adrenergic receptors
B. Dopaminergic receptors
C. Beta 2 receptors
D. Opioid receptors
Beta 2 agonist causes ____?
A. Mydriasis
B. Contraction of urinary spinctors
C. Vasoconstriction
D. Bronchial muscle relaxation
The following drugs are avoided with warfarin __?
A. Antacids
B. Benzodiazepine
C. Nsaid’s like Ibuprofen
D. Codeine, dihydrocodeine, paracetmol
The drug of choice in the management of life threatening allergic reaction is ____?
A. Corticosteroids
B. Antihistamines
C. Adrenalin
D. Diazepam
The drug which is used to treat laryngospasm is _____?
A. Atropine
B. Diazepam
C. Neostigmine
D. Succinylcholine
Pilocarpine ______?
A. Lowers the intraocular pressure in glaucoma
B. Cleaved by acetylcholinesterase
C. Inhibits sweat and lacrimation
D. Causes tachycardia
An excess of which of the following hormones may be associated with increased sensitivity to epinephrine ?
A. Testosterone
B. Parathyroid
C. Insulin
D. Thyroid
The antidote for heparin is ______?
A. Penicillinase
B. Protamine sulphate
C. Pryosulphate
D. Potassium sulphate
Which of the following is not an action of epinephrine when administered intravenously in a high dose ?
A. Increased liver glycogenolysis
B. Causes broachiolar constriction
C. Evokes extrasystoles in the heart
D. Produces restlessness and anxiety
Delay in blood coagulation results from _____?
A. Human thrombin
B. Heparin
C. Ferric chloride
D. Vit-K
Heparin, apart from releasing lypoprotein lipase in the blood exerts its anti-coagulant action by _____?
A. Binding to calcium
B. Inhibiting fibrinogen synthesis
C. Inhibiting prothrombin synthesis
D. Inhibiting thrombin synthesis
Excessive bleeding due to heparin overdose is controlled by _____?
A. Protamine sultate
B. Vitamin K
C. Factor VIII
D. EADA
Warfarin therapy is prolonged by all except _____?
A. Rifampicin
B. Amoxycillin
C. Erythromycin
D. Tetracycline
Which of the following is a vosoconstrictor ____?
A. Bupivacaine
B. Procaine
C. Lidocaine
D. None of the above
Steroids ____?
A. Steroids reduce the rate of repair of tissues thus delays the healing
B. Exacerbate the inflammatory response
C. Can be safely given to immunocompromised patients
D. Indicated in oral thrush
Which of the following drugs is not hypoglycemic?
A. Ethosuxinide
B. Tolbutamide
C. Glibenclamide
D. Gluengon
The highest risk associated with use of oral contraceptives in ______?
A. Hepatic necrosis
B. Permanent sterility
C. Thromboembolic disorders
D. Cancer of breast
Identify the factors which decrease the effect of Oral anticoagulants _____?
A. Pregnancy
B. Nephrotic syndorme
C. Newborn
D. Liver disease
E. Both A & B
The anticogulant of choice during pregnancy is _____?
A. Warfarin sodium
B. Sodium oxalate
C. Heparin
D. Phenindone
Rebound phenomenon is most commonly seen with use of ______?
A. Epinephrine
B. Norepinephrine
C. Phenyleprine
D. Leuonordefrin
If patient is given Noradrenaline what will happen ______?
A. Cause increase in B.P, due to its action on Beta receptors only
B. Cause decrease in B.P, due to its action on Alpha receptors only
C. Cause decrease in cardiac output and relax bradycardia
D. None of the above
various insulin preparations useful in the treatment of diabetes mellitus differ primarily in _____?
A. Focus of action
B. Onset and duration of action
C. Mode of biotransformation
D. None of the above
Bleeding from the oral mucosa can be reduced by topical use of _____?
A. Epinephrine
B. Lidnocaine
C. Hydrocortisone
D. Dicoumarol
A person with glaucoma should not receive _____?
A. Sedatives
B. Vasoconstrictors
C. Antisialogogues
D. Local anaesthetic
Dry mouth during antidepressant therapy is caused by blockade of __?
A. Muscarinic acetylcholine receptors
B. Serotonergic receptors
C. Dopaminergic receptors
D. GABA receptors
Which one of the following drugs is not a non depolarizing competitive neuromuscular blocker ?
A. Doxacurim
B. Decamethonium
C. Rocuronium
D. Mivacurium
Therapeutic uses of a – adrenoceptor blockers include all of the following EXCEPT ______?
A. Hypertension
B. Amxiety
C. Peripheral Vascular disease
D. Benign Prostatic hypertrophy
All of the following are endogenous corticosteriods released by all adrenal cortex EXCEPT ____?
A. Cortisol
B. Cortisone
C. Dexamethsone
D. Aldosterone
Which of the following synthetic sterioid shows predominantly mineralocorticoid action ?
A. Hydrocortisone
B. Spironolactone
C. Dexamethsone
D. Fludrocortisone
Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus ______?
Curare poisoning is characterised by _______?
A. Hypertension
B. Hypotension
C. Doesn’t release histamine
D. Oral route of administration is the best route
Which one of the following does NOT act by increasing insulin secretion ______?
A. Glyburide
B. Repaglinide
C. Tolbutamide
D. Biguanide
Which one of the following agents/ drugs is of no value in the post operative care of the hemophiliac patient ?
A. Tranexamic acid
B. Clopidogrel
C. Aminocarproic Acid
D. Factor VIII cryoprecipitate
All of the following have receptors which are transcription factors except _____?
A. Insulin
B. Estrogen
C. Vitamin D
D. Glucocorticoid
Adrenaline is used in following EXCEPT _____?
A. With xylocaine
B. Post extraction socket
C. Anaphylactin shock
D. Angina in dental chair
E. Both B & D
Sialogouges are _____?
A. Increases salivary secretions
B. Decrease salivary secreations
C. Indicator dye for sialography
D. Medication for over function
A patient taking beta-blocker preoperatively, at induction of anaesthesia with fentanyl. Which muscle relaxant should be avoided ?
A. Pancuronium
B. Rocuronium
C. Vecuronium
D. Atracurium
All are true about metformin except ______?
A. Inhibits cellular respiration in mitochondria
B. Excreted unchanged in urine
C. Reduce hepatic glucose production
D. Used in decompensated heart failure
Succinylcholine is a/an _____?
A. Intravenous anaesthetic agent
B. Non-depolarizing muscle relaxant
C. Short-acting narcotic
D. None of the above
Which of the following receptors is activated by acetylcholine and blocked by atropine ____?
A. Nicotinic
B. Muscarinic
C. Alpha 1 and 2
D. Beta 1 and 2
Which of the following is a peripherally acting muscle relaxant _____?
A. Chlorozoxazone
B. Methocarbomol
C. Succinyl choline
D. Cortisopradol
The drug which is contraindicated in haemophilla is _____?
A. Aspirin
B. Penicillinium
C. Amino epsilon caproic acid
D. Dipheny 1 hydantoin
Which of the following is NOT an important/frequent/well-known manifestation of an adverse drug reaction ?
A. Agranulocytosis
B. Aplastic anaemia
C. Aaemolysis
D. Leukaemia
Fellypressin is a ______?
A. Vaso dilator
B. Vaso constrictor
C. Neuroleptic
D. Anti coagulant
Succinylcholine prevents bronchospasm by ______?
A. Depolarising block
B. Direct muscle relaxation
C. Centrally acting muscle relaxation
D. Dual action
Short-acting non-depolarising muscle relaxant is ______?
A. Succinylcholine
B. Pancuronium
C. Mivacurum
D. Decamethonium
Scopolamine helps in ______?
A. Motion sickness
B. Hypertension
C. Decreased secretions
D. A & C
In which of the following categories are ephedrine, tyramine and emphetamine classified ______?
A. Anticholinesterases
B. Alpha-adrenergic blocking agents
C. Indirect acting sympathomimetics
D. Direct acting sympathomimetics
Agents/Drugs which help in rapid coagulation of Blood ____?
A. Astrigents
B. Styptics
C. Haemostatics
D. All of the above
Triflusal is a ______?
A. Anti-inflaqmmatory drug
B. Antibiotic
C. Anti-arthritic drug
D. Antiplatelet drug
The anticoagulant action of Warfarin is potentiated by all except ____?
A. Phenylbutazone
B. Vitamin K
C. Rifampicin
D. B & C
Which of the following statements is not correct regarding warfarin ______?
A. Transient hypercoagulability is seen
B. Better avoided during pregnancy as it may causes skeletal deformity of the foetus
C. In a racemic mixture the R form is four times more active than the S form
D. The anticoagulant effect is seen only after 72 hours of administration
Morphine withdrawal is characterized by all EXCEPT ____?
A. Miosis
B. Yawning
C. Lacrimation
D. Diarrhoea
All of the following are true about tolbutamide except ____?
A. It is taken orally
B. It is used in type-I diabetes mellitus
C. It causes alcohol intolerance
D. It acts on pancreas to stimulate release of insulin
An oral hypoglycemic agent is ______?
A. Warfarin
B. Insultin
C. Glibeneclamide
D. Gluengon
Role of Heparin ____?
A. Prevents synthesis of prothrombin
B. Prevents synthesis of fibrinogen
C. Prevents conversion of fibrinogen to fibrin
D. Prevents prothrombin conversion to thrombin
The drug which activates plasma antithrombin -III for its anticogulant action is _____?
A. Dicumarol
B. Idphenadione
C. Heparin
D. Phenindone
Which of the following drugs is used therapeutically during allergic conditions ?
A. Epinephrine
B. Succinylcholine
C. Tetracycline
D. Sulfonamides
Which one of the following can be blocked by atropine ?
A. Decreased blood pleasure caused by hexamethonium
B. Increased blood pressure caused by nicotine
C. Tachycardia caused by exercise
D. Tachycardia caused by infusion of acetylcholine
Atropine is used in _____?
A. Organophosphate poisoning
B. Chronic glaucoma
C. Syncope
D. Trigeminal neuralgia
In treating Xerostomia, Which of the following might be prescribed ?
A. Atropine
B. Neostigmine
C. Scopalamine
D. Ephedrine
Which one of the following drugs is not a reversible anticholinesterase drug ?
A. Edrophonium
B. Demecarium
C. Carbaryl
D. Tacrine
Which of the following drugs undergoes “Hoffmann elimination” ?
A. d-tubecurarine
B. Acetycholine
C. Atracurium
D. Acetazolamide
Which of the following general anesthetics is given by intravenous route ?
A. Propofol
B. Sevofluorane
C. Naloxane
D. Flumizenil
D-tubocurarine blocks the neuromuscular transmission by ___?
A. Blocking acetylcholine receptors
B. Prevent release of acetyl choline
C. Destroys acetyl choline
D. Inactivate acetylcholine esterase enzyme
Which of the following combination of iron can be given both IM and IV ____?
A. Iron dextran
B. Iron Sorbitol Citrate Solution
C. ferrous Sulphate
D. ferrous Humourate
The toxic effect of Beta receptor antagonists includes all the following EXCEPT ______?
A. Hypoglycemic episodes in diabetes
B. Worsening of preexisting asthma
C. Ischemic cardiac episode on abrupt discontinuation
D. Precipitate migrainic effect
Drugs causing hyperglycemia _____?
A. B-blocker
B. Glucocorticoids
C. Acetylcholine
D. a-blockers
Cloidogrel is an _____?
A. Anti hypertensive
B. Antidiabetic
C. Antipalatelet
D. Anticoagulant
All are true about nitric oxide, EXCEPT ___?
A. Regulates vasomotor tone
B. Acts via cAMP
C. Present in cigarette smoke
D. It is important in penile erection
Mode of action of sulphonyl ureas includes all the following except ______?
A. Activating receptors on beta cells of pancreas to release insulin
B. Inhibiting gluconeogenesis in liver
C. Enhancing insulin mediated post receptor enzyme reaction
D. Decreasing Glucose absorption from the qut
All of the following glucocorticorticoids can be given by inhalation EXCEPT ____?
A. Dexamethasone
B. Beclomethasone
C. Budesonide
D. Fluticasone
Which is NOT a 2nd generation antihistaminic ?
A. Loratidine
B. Acrivastatine
C. Cyclizine
D. Terfenidine
A patient is having bronchodilation, increased temperature, constipation and tachycardia. The tentative diagnosis is ______?
A. Oraganophosphate poisoning
B. Paracetamol poisoning
C. Mushroom poisoning
D. Atropine poisoning
The principle therapeutic action of the glucocorticoid is ______?
A. Antidiuretic
B. Antianabolic
C. Anti-infective
D. Anti-inflammatory
Indirect sympathomimetics can _____?
A. Penetrate the blood brain barrier
B. Cause euphoria
C. Both of the above
D. None of the above
Read More: Past Papers of Pharmacology